The Ovarian Blood Follicle Barrier Is Both Charge- and Size-Selective in Mice1
نویسندگان
چکیده
منابع مشابه
The molecular basis of selective permeability of connexins is complex and includes both size and charge.
Although gap junction channels are still widely viewed as large, non-specific pores connecting cells, the diversity in the connexin family has led more attention to be focused on their permeability characteristics. We summarize here the current status of these investigations, both published and on-going, that reveal both charge and size selectivity between gap junction channels composed of diff...
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Buffaloes are well known domestic animals in Asia, Mediterranean and Latin American countries of the world for different breeding purposes such as milk, meat, draught and capital [23]. The buffalo has been regarded as poor reproductive efficiency and characterized by low conception rates [6, 22, 23]. Seasonality of buffalo breeding results in a milk supply that exceeds demand in summer and autu...
متن کاملSize-selective loosening of the blood-brain barrier in claudin-5–deficient mice
Tight junctions are well-developed between adjacent endothelial cells of blood vessels in the central nervous system, and play a central role in establishing the blood-brain barrier (BBB). Claudin-5 is a major cell adhesion molecule of tight junctions in brain endothelial cells. To examine its possible involvement in the BBB, claudin-5-deficient mice were generated. In the brains of these mice,...
متن کاملSize-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1.
The vasculature of the central nervous system (CNS) forms a selective barrier termed the blood-brain barrier (BBB). Disruption of the BBB may contribute to various CNS diseases. Conversely, the intact BBB restricts efficient penetration of CNS-targeted drugs. Here, we report the BBB-regulatory role of endothelial sphingosine 1-phosphate (S1P) receptor-1, a G protein-coupled receptor known to pr...
متن کاملThe bovine dominant ovarian follicle.
Central roles in reproductive biology (i.e., growth and development of the oocyte, steroidogenesis, and ovulation) are played by the ovarian dominant follicle (DF). The DF is different from other follicles because it can escape atresia (the fate of all other follicles), and if exposed to the LH surge, its cells will differentiate into the corpus luteum. The DF was originally studied by looking ...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1998
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod58.3.705